Immune & Antiviral Support

UVBI Treatment: Ultraviolet Blood Irradiation Therapy

At Unchained Psychiatry & Wellness, we offer UVBI treatment as part of a broader approach to immune support and recovery from chronic infections. Ultraviolet blood irradiation therapy is not new. It has actually been used clinically for decades, and honestly, that track record matters. We use it today as a complementary therapy for patients whose immune systems are just struggling to keep up.

Ultraviolet Blood Irradiation
How the Therapy Works

A small amount of blood is exposed to ultraviolet light, then returned to your body through an IV line — inactivating pathogens and modulating your immune response.

UVBIUltraviolet blood irradiation
UV LightInactivates viruses & bacteria
Clinician-administeredSupervised medical setting
Decades
Of Clinical Use
5+
Conditions Supported
Clinical
Setting Only
IV-Line
Blood Returned

That might look like a persistent infection that keeps coming back. It might be an autoimmune flare, or maybe the lingering aftermath of a virus that never seemed to fully resolve. You know that feeling where you never quite got back to baseline? That is exactly the kind of situation where UVBI tends to come up in conversation.

If standard treatment has left you without answers, this page walks through what UVBI is, who it tends to help, and how we approach it here at our professional wellness services clinic. We want you to have a more complete picture before you decide what feels right for your body.

What It Is

What Is UVBI Treatment?

The essentials
  • Small blood draw
  • Ultraviolet light chamber
  • Returned through an IV line
  • Supervised medical setting

UVBI stands for ultraviolet blood irradiation. During the procedure, we draw a small amount of your blood, pass it through a chamber that exposes it to ultraviolet light, and then return the treated blood to your body through an IV line. The exposure to UV light inactivates viruses and harmful bacteria present in the blood sample while also triggering changes in your white blood cells that can improve how your immune system responds to ongoing infection.

The therapy is administered in a supervised medical setting from start to finish. It is not a standalone cure, and we do not present it as one. It works best as part of a broader treatment plan that may include IV therapy, nutrient support, or ozone therapy, depending on what your body needs.

How It Works

How Ultraviolet Blood Irradiation Works

At the Cellular Level
Pathogens Damaged, Cells Modulated

Once your blood is exposed to ultraviolet light, several things happen at the cellular level. Harmful pathogens, including certain bacteria and viruses, are damaged or deactivated as they pass through the UV chamber. Your red blood cells and white blood cells are affected differently by this exposure, and that difference is part of why the therapy has an immune-modulating effect rather than simply a sterilizing one.

Back in Circulation
A Body Ready to Fight Back

The treated blood, once returned to circulation, appears to help your immune system recognize threats it had been struggling against. Many patients describe this as their body finally being able to fight back. We often pair UVBI with ozone therapy, since ozone improves how your cells use oxygen and further reduces inflammation, giving you a layered approach that addresses both the infection itself and your body's capacity to respond to it.

Who It Helps

Who Benefits from UVBI Therapy

UVBI therapy tends to help patients dealing with chronic infections that have not responded well to standard treatment. This includes people who have completed a full course of antibiotics for Lyme disease and still feel unwell, patients managing the exhaustion of Epstein-Barr virus or chronic fatigue, and those recovering from a shingles outbreak who want to reduce nerve inflammation and shorten how long symptoms last.

We also see patients with autoimmune conditions such as rheumatoid arthritis, where the goal is not eliminating an infection but calming an overactive immune response and reducing systemic inflammation. If your blood work and history point toward one of these patterns, UVBI may be a reasonable addition to your care.

Common Situations

Common Situations That Bring Patients to UVBI

Most people who come to us for UVBI treatment have already tried the standard route. They have taken antibiotics, waited out a virus, or managed an autoimmune flare with medication, and they are still dealing with fatigue, pain, or symptoms that will not fully resolve. Others come to us after a Long COVID diagnosis, looking for support with the brain fog and low energy that followed their initial illness.

A smaller group of patients comes in proactively, wanting to support their immune system before an infection becomes chronic, particularly if they have a history of autoimmune disease or repeated illness. Here are the conditions we most often use UVBI and ozone therapy to support:

  • Lyme disease, including chronic and post-treatment cases
  • Epstein Barr virus and chronic fatigue syndrome
  • Shingles, both acute outbreaks and post-herpetic nerve pain
  • Long COVID and other post-viral syndromes
  • Autoimmune conditions such as rheumatoid arthritis and lupus
Your Session

What to Expect During Your UVBI Session

01Consultation
Consultation & Protocol Design

Your first visit starts with a consultation where our clinical team reviews your history, current symptoms, and any relevant lab work. From there, we design a protocol specific to your condition rather than running everyone through the same number of sessions.

02Procedure
The Procedure Itself

The procedure itself is straightforward. We draw a small amount of your blood, pass it through the UV chamber, and, in many protocols, follow it with an ozone infusion before returning the treated blood to your body. You will have a brief observation period afterward, and most patients resume their normal activities the same day.

03Cadence
How Many Sessions

Acute conditions like shingles often respond within just a few sessions, while chronic infections such as Lyme disease typically call for a longer protocol, sometimes eight to twelve treatments or more, coordinated with supporting IV therapies.

Why Us

Why Patients Choose Us for UVBI and Ozone Therapy

Clinical
Clinical, Not a Spa Add-On

We administer UVBI and ozone therapy in a clinical setting with trained medical staff overseeing every step, not as an add-on service in a spa environment. Our team treats this therapy the way we treat every service we offer, by starting with an evaluation and building a plan around your actual condition rather than a fixed package.

Coordinated
Part of a Coordinated Plan

Because UVBI works best as part of a coordinated plan, we frequently combine it with other therapies from our Longevity and Vitality IV Center, particularly when a patient's fatigue or inflammation calls for more support than UVBI alone can provide.

Related Therapies

Related Therapies That Support Your Treatment Plan

UVBI rarely works in isolation, and we do not treat it that way. Patients dealing with chronic fatigue often benefit from pairing UVBI with NAD+ or high-dose vitamin C, since these support cellular energy and antioxidant capacity while UVBI addresses pathogen load. Glutathione is another common addition, particularly for patients focused on detoxification and reducing oxidative stress alongside their immune support protocol.

If your fatigue, brain fog, or inflammation are connected to a Long COVID diagnosis, or if your case fits the pattern of chronic fatigue we described earlier, those condition-specific pages go into more depth on how we approach treatment for each situation. For patients in the Gilbert area specifically, our UVBI Treatment in Gilbert, AZ covers the same clinical protocol with details on scheduling and access for local patients.

Get Started

Scheduling Your UVBI Consultation

UVBI and ozone therapy are generally self-pay services since they are considered integrative treatments rather than standard covered procedures. Session pricing and package details are available on our pricing page, and our team is happy to walk you through the cost before you commit to a protocol.

If you are dealing with a chronic infection, an autoimmune flare, or lingering symptoms from a past illness, the next step is a consultation with our clinical team. We will review your history, discuss whether UVBI fits your situation, and build a protocol around what your body actually needs. You can reach us directly through our contact page or call (480) 536-9473 to get started.

Ready to find out whether UVBI fits your situation? Our clinical team will review your history and build a protocol around what your body actually needs.

Contact Us
Real Stories

Real Stories, Life Changing Results

At Unchained Psychiatry & Wellness, we are honored to have helped many individuals on their journey to mental wellness. Here are some testimonials from our patients:

No Referral Required
Ready to Talk Through UVBI?

Our clinical team will review your history and build a UVBI protocol around your specific infection, autoimmune, or post-viral symptoms.